MyFitFuel L-Arginine Alpha Ketoglutarate (AAKG) Protein (200gm, Unflavored) Price in India, Specifications, Reviews & Offers. Buy online @ Flipkart Amazon.

What you just have to do is make your organism do all the work for you. Pay attention: if you want a routine that will take less than 5 minutes per day, just try gooogling Simmy Krotiel's homepage and good luck. 2-4 in . longer might not be much, yet certainly feasible.
What you just have to do is make your organism do all the work for you. Pay attention: if you want a routine that will take less than 5 minutes per day, just try gooogling Simmy Krotiel's homepage and good luck. 2-4 in . longer might not be much, yet certainly feasible.
I think you should publish a book "Longevity and how to obtain it". Your knowledge is outstanding. Publish on Audio Books so I can listen as I go to sleep...great work.
Thank you ✨❤️✨
Wicked Smaht !!!
If we should be hindering DNA methylation as Dr Kennedy stated in regard to the AKG results, then if we take TMG to prevent methylation deficiency when we take niacin or NMN, then could we have excess methylation activity if we overshoot? https://www.longevity.technology/age-of-resistance-as-clever-supplement-holds-back-biological-aging/
I'm getting conflicting information, so the ref above from the Dr. Kennedy Lab shows AKG inhibits TOR, but I saw another study showing the opposite,"low-protein diets supplemented with AKG enhanced serum and intramuscular free AA concentrations, the mRNA abundances of AA transporters, and serum concentrations of insulin-like growth factor-1 (IGF-1), activated the mammalian target of rapamycin (mTOR) pathway" (doi: 10.1007/s00726-018-2618-3.). It seems contradictory that AKG would facilitate lifespan extension since it activates mTOR which shortens lifespan, though it enhances tissue repair, muscle growth, etc. , an effect similar to branched chain amino acids. These are at odds with lifespan extension though one can argue it helps with healthspan improvement, but at a possible cost for increased lifespan? Can someone explain this? here's anotehr study showing AKG mTOR effects: J Nutr . 2016 Aug;146(8):1514-20. doi: 10.3945/jn.116.236000. Epub 2016 Jul 6. Dietary Supplementation with α-Ketoglutarate Activates mTOR Signaling and Enhances Energy Status in Skeletal Muscle of Lipopolysaccharide-Challenged Piglets Lei Wang 1, Dan Yi 1, Yongqing Hou 2, Binying Ding 1, Kang Li 1, Baocheng Li 1, Huiling Zhu 1, Yulan Liu 1, Guoyao Wu 3
Actually, the same health improvement can be achieved for peanuts by taking more than 2 g of citric acid or any citrate per day. AKG can be produced in our body from citrates. And indeed, if to use citric acid with meat, the advantage will be better protein digestion. Or with water - it also will help but in lesser extent.
Can AAKG have same effect?
From my understanding those inflammatory markers are secreted by senescent cells to signal our body to get rid of it. Wouldn't the suppression of this secretion caused by AKG supplementation cause a net accumulation of senescent cells theoretically?
Too many...
I'm concerned about the glutamine-generating aspect of AKG. Could it contribute to cancer growth? Also, there's this: "... enhanced GLN [glutamine] synthesis may exert adverse effects in the brain (swelling of astrocytes or altered neurotransmission) and stimulate catabolism of branched-chain amino acids (BCAA; valine, leucine, and isoleucine) in skeletal muscle. Furthermore, the majority of GLN produced is released to the blood and catabolized in enterocytes and the kidneys to ammonia, which due to liver injury escapes detoxification to urea and appears in peripheral blood. As only one molecule of ammonia is detoxified in GLN synthesis whereas two molecules may appear in GLN breakdown, these events can be seen as a vicious cycle in which enhanced ammonia concentration activates synthesis of GLN leading to its subsequent catabolism and increase in ammonia levels in the blood." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930847/ What did the mice die of, exactly?
Thanks Eleanor! This video is so well made! nice and simple! By the way I am the first author of the paper!
Wrong information. Ca form is unavailable to anyone except research scientists. It has not been used in humans, only lab rats. Use caution. It's dangerous for humans as far as we know.
Shut up and tell me where to buy this CaAKG!
Is there a big difference between the effect of Ca-AKG and AAKG?
Which form is more effective? Glutamine-AKG or Arginine-AKG?
Hey so where can I buy it in the correct form? I can find it as ornithine and Argentine but not as a calcium salt as was used in the experiment!
hey Eleanor, I wonder: every time some lab discover something new, you guys that are already in the field are something like in the VIP area, what means you people in this biomedical field are always 100 steps forward compared to us mere mortals, that live in the dark. But how much of newspapers in the aging field really affect how you live? I think I saw somewhere that you already take some supplements related to aging healthier, but I don't remember where. I know it's very personal but does be in the field really gives you an advantage compared to people in other areas, or new discoveries don't affect your life at all, maybe because you don't care? Do you see any difference in healthy and aging compared to people around you? Not being rude, its pure curiosity. And that is not the time to be modest, .
Would you recommend taking the Calcium-AKG in capsule form as in the rejuvenate capsules or directly in powder form? Which do you think would be better?
hey sheekey, have you decided what you want to do in life, I mean, what you will specialize him?
Wow, really great video explaining the study. Thanks for making it!
SuperLike 👍
I used for 4 months and i have more energy and a good body. *It works*
I love AAKG have not used this the now one but I love the quicker recovery time.