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thanks Great job Thanks Thanks a lot .. Asslam o alikam sir plz explain in urdu Sir hindi me video banavo,mare ma ko yahi disorder hai,kya iska ilaj ho sakta hai nice one..thanks Can all this available with prepladder app Early onset of Alzheimers is not associated with ApoE4 rather thn Early-onset AD follows an autosomal dominant inheritance pattern related to mutations in genes that alter amyloid beta protein production, aggregation, or clearance, including amyloid precursor protein (APP), presenilin 1 (PSEN1), and presenilin 2 (PSEN2) and genetic risk factor for late-onset AD is APOE; carriers of one e4 allele are at two- to threefold increased odds of developing AD compared with noncarriers, and those with two e4 alleles are at approximately 8- to 12-fold increased odds and i think you said here in reverse sir plz correct me if am wrong Isme kis medicin ka use hota hai hardworking man ...... nice one mathab sir nice .keep it up Very effective video guru ji